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tecovirimat will raise the degree or impact of diazepam by influencing hepatic enzyme CYP2C19 metabolism. Use Caution/Watch. Tecovirimat is actually a weak inhibitor of CYP2C8 and CYP2C19. Observe for adverse outcomes if coadministered with delicate substrates of those enzymes.Use VALTOCO precisely as your Health care company prescribed. Bodily dep